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gemcitabine

Product Name
gemcitabine
CAS No.
103882-84-4
Chemical Name
gemcitabine
Synonyms
C056507;2',2'-Dfdc;2'-Deoxy-2'-difluorocytidine;Gemcitabine, (alpha-D-threo-pentofuranosyl)-isomer;2'-Deoxy-2',2''-difluorocytidine-5'-o-monophosphate;4-?amino-?1-?(2-?deoxy-?2,?2-?difluoro-?D-?erythro-?pentofuranosyl)?-2(1H)?-?Pyrimidinone
CBNumber
CB71361011
Molecular Formula
C9H11F2N3O4
Formula Weight
263.2
MOL File
103882-84-4.mol
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gemcitabine Property

Boiling point:
482.7±55.0 °C(Predicted)
Density 
1.4034 (estimate)
solubility 
DMSO (Slightly), Methanol (Slightly)
form 
Solid
pka
11.65±0.70(Predicted)
color 
White
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC
Product number
G305030
Product name
2’,2’-Difluoro-2’-deoxycytidine
Packaging
500mg
Price
$60
Updated
2021/12/16
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gemcitabine Chemical Properties,Usage,Production

Uses

Gemcitabine is a nucleoside analog with anti-cancer properties. An inhibitor of DNA synthesis active on solid tumors.

Definition

ChEBI: Gemcitabine is a 2'-deoxycytidine having geminal fluoro substituents in the 2'-position. An inhibitor of ribonucleotide reductase, gemcitabine is used in the treatment of various carcinomas, particularly non-small cell lung cancer, pancreatic cancer, bladder cancer and breast cancer. It has a role as a photosensitizing agent, a DNA synthesis inhibitor, a prodrug, an EC 1.17.4.1 (ribonucleoside-diphosphate reductase) inhibitor, an environmental contaminant, a xenobiotic, a radiosensitizing agent, an antineoplastic agent, an antimetabolite, an antiviral drug and an immunosuppressive agent. It is an organofluorine compound and a pyrimidine 2'-deoxyribonucleoside.

gemcitabine Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from gemcitabine manufacturers

Hebei Mingeng Biotechnology Co., Ltd
Product
Gemcitabine 103882-84-4
Price
US $200.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
1000kg/Month
Release date
2022-11-25
Shijiazhuang Gantuo Biotechnology Co., Ltd
Product
gemcitabine 103882-84-4
Price
US $100.00/mg
Min. Order
25mg
Purity
99%
Supply Ability
1000g
Release date
2023-03-10

103882-84-4, gemcitabineRelated Search:


  • 2',2'-Dfdc
  • 2'-Deoxy-2',2''-difluorocytidine-5'-o-monophosphate
  • 2'-Deoxy-2'-difluorocytidine
  • C056507
  • Gemcitabine, (alpha-D-threo-pentofuranosyl)-isomer
  • 4-?amino-?1-?(2-?deoxy-?2,?2-?difluoro-?D-?erythro-?pentofuranosyl)?-2(1H)?-?Pyrimidinone
  • 103882-84-4